The laser multi-coordinate measuring system has the advantages of high precision and wide measuring range and has wide application prospects in the fields of large-scale high-precision coordinate measurement. In order to improve the coordinate measurement accuracy of the laser multi-coordinate measuring system, the influence of station layout on measurement accuracy is quantitatively analyzed, meanwhile, and the influence of the positional relationship between the measuring equipment and the measured point on the uncertainty of coordinate measurement is introduced too. Speaker(s): DONGJING, Virtual: https://events.vtools.ieee.org/m/320887